Symbol
Name
ID

Zbtb16
zinc finger and BTB domain containing 16
MGI:103222

Phenotype annotations related to reproductive system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Metrorrhagia
Disease(s) Associated with ZBTB16	Metrorrhagia
acute promyelocytic leukemia

Mouse Phenotypes

reproductive system phenotype

azoospermia

oligozoospermia

abnormal spermatogonia morphology

decreased male germ cell number

abnormal male germ cell apoptosis

increased male germ cell apoptosis

asthenozoospermia

abnormal spermatogonia proliferation

abnormal testis morphology

seminiferous tubule degeneration

increased Leydig cell number

small testis

testicular atrophy

abnormal spermatogenesis

male infertility

reduced male fertility

Availability

Mouse Genotype

Zbtb16^7t/Zbtb16^7t

Zbtb16^em1(IMPC)Mbp/Zbtb16^em1(IMPC)Mbp

Zbtb16^lu-Sfd/Zbtb16^lu-Sfd

Zbtb16^lu/Zbtb16^lu

Zbtb16^pnky/Zbtb16^pnky

Zbtb16^tm1Geno/Zbtb16^tm1Geno

Zbtb16^tm1Ppp/Zbtb16^tm1Ppp

Zbtb16^tm2Geno/Zbtb16^tm2Geno

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23